AGA Antibody | 15-281

AGA Antibody | 15-281 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse

Homology: N/A

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 24-346 of human AGA (NP_000018.2) .

Research Area: Other

Tested Application: WB, IF

Application: WB: 1:500 - 1:1000
IF: 1:50 - 1:100

Specificiy: N/A

Positive Control 1: SW620

Positive Control 2: THP-1

Positive Control 3: HepG2

Positive Control 4: Mouse liver

Positive Control 5: Mouse pancreas

Positive Control 6: N/A

Molecular Weight: Observed: 18kDa

Validation: N/A

Isoform: N/A

Purification: Affinity purification

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Concentration: N/A

Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.

Alternate Name: AGU, ASRG, GA, N (4) - (beta-N-acetylglucosaminyl) -L-asparaginase, N4- (N-acetyl-beta-glucosaminyl) -L-asparagine amidase, aspartylglucosylamine deaspartylase, glycosylasparaginase

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: This gene encodes a member of the N-terminal nucleophile (Ntn) hydrolase family of proteins. The encoded preproprotein is proteolytically processed to generate alpha and beta chains that comprise the mature enzyme. This enzyme is involved in the catabolism of N-linked oligosaccharides of glycoproteins. It cleaves asparagine from N-acetylglucosamines as one of the final steps in the lysosomal breakdown of glycoproteins. Mutations in this gene are associated with the lysosomal storage disease aspartylglycosaminuria that results in progressive neurodegeneration. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is subject to proteolytic processing.