AGFG1 polyclonal Antibody | BS8106

AGFG1 polyclonal Antibody | BS8106 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse

Application: WB IF

Application Range: WB: 1:500~1:2000 IF: 1:50~1:200

Background: HIV-1 Rev is the prototype of a class of retroviral regulatory proteins that control the sequence-specific nuclear export and translation of a class of incompletely spliced HIV-1 mRNAs that encode viral structural proteins. In the absence of Rev, these late viral RNAs remain sequestered in the nucleus until they are either spliced or degraded. The protein designated Rev interacting protein (RIP) or Rev/Rex activation domain-binding protein (Rab) contains 562 amino acids. RIP/Rab has been identified as a cellular cofactor that binds not only to the HIV-1 Rev activation domain, but also to equivalent domains of other Rev and Rex proteins. On the basis of these findings it has been speculated that RIP/Rab is required for the Rev response and thus for HIV-1 replication.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: AGFG1 polyclonal Antibody detects endogenous levels of AGFG1 protein.

Molecular Weight: ~ 58 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Arf-GAP domain and FG repeat-containing protein 1; HIV-1 Rev-binding protein; Nucleoporin-like protein RIP; Rev-interacting protein; Rev/Rex activation domain-binding protein; AGFG1; HRB; RAB; RIP

Immunogen: Recombinant full length Human AGFG1.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: