AGR2 polyclonal Antibody | BS90038

AGR2 polyclonal Antibody | BS90038 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human

Application: WB ICC IHC IP FC

Application Range: WB:1:1,000-1:5,000 ICC:1:100-1:500 IHC:1:50-1:200 FC:1:50-1:100

Background: AGR2 (Anterior Gradient Protein 2), also known as AG2, GOB-4 or HAG-2, is a member of the anterior gradient homolog family. It is the human ortholog of XAG-2, the secreted Xenopus laevis Anterior Gradient protein. In X. laevis, it is involved in cement gland differentiation and neural marker gene expression. AGR2 is a secretory protein encoded by two different AGR2 transcripts. It interacts with LYPD3 and α-dystroglycan (DAG-1) . AGR2 is ubiquitously expressed with up-regulated expression in prostate cancer, breast cancer, lung cancer, renal carcinomas and endometrial carcinomas. AGR2 expression is positively correlated with that of the estrogen receptor (ER) and is negatively correlated with that of the epidermal growth factor receptor (EGFR) . AGR2 may serve as a potential therapeutic marker for various cancers.

Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity: AGR2 polyclonal Antibody detects endogenous levels of AGR2 protein.

Molecular Weight: 17 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: AG-2, hAG-2, AGR2, AG 2, AG 2 protein, AG-2, AG2, AG2 protein, AGR 2, AGR2, AGR2, Anterior gradient 2 homolog (Xenopus laevis), anterior gradient 2 homolog, Anterior gradient 2, Xenopus, homolog of, Anterior gradient homolog 2, Anterior gradient protein 2 homolog, GOB 4, GOB4, HAG 2, hAG-2, hAG2, HAG2/R, HPC 8, hPC8, PDIA17, Protein disulfide isomerase family A member 17, secreted cement gland homolog, Secreted cement gland protein XAG 2 homolog, Secreted cement gland protein XAG-2 homolog, Secreted cement gland protein XAG2 homolog, XAG 2, XAG2,

Immunogen: recombinant protein

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: ProA affinity purified

Pathway: