AKAP12 Polyclonal Antibody | E-AB-12884

AKAP12 Polyclonal Antibody | E-AB-12884 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: A kinase (PRKA) anchor protein (gravin) 12, A kinase Anchor Protein 12, A kinase anchor protein 250kDa, A-kinase anchor protein 12, A-kinase anchor protein 250 kDa, AKA12, AKAP 12, AKAP 250, AKAP-12, Akap12, AKAP250, DKFZp686M0430, DKFZp686O0331, FLJ20945, FLJ97621, Gercelin, Gravin, Kinase scaffold protein gravin, Myasthenia gravis autoantigen, Myasthenia gravis autoantigen gravin, OTTHUMP00000017426, OTTHUMP00000017427, Src-Suppressed C Kinase Substrate, Srcs5, SSeCKS, Tsga12

Application: IHC, ELISA

Reactivity: Human

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Neuroscience, Signal Transduction

Background: The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is expressed in endothelial cells, cultured fibroblasts, and osteosarcoma cells. It associates with protein kinases A and C and phosphatase, and serves as a scaffold protein in signal transduction. This protein and RII PKA colocalize at the cell periphery. This protein is a cell growth-related protein. Antibodies to this protein can be produced by patients with myasthenia gravis. Alternative splicing of this gene results in two transcript variants encoding different isoforms.

Concentration: 0.4 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Synthetic peptide of human AKAP12

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: IHC 1:50-1:200

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): N/A

Molecular Weight(Observed): N/A