400

AKT1 Antibody (pSer473)- RPE

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SKU:
400-SPC-1340D-RPE-GEN
Availability:
IN STOCK
NULL642.00

Description

Rabbit Anti-Human AKT1 (pSer473) Polyclonal

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Additional Information

Size:
100 µl
Target:
AKT1 (pSer473)
Conjugate:
RPE
Research Area:
Cell Signaling | Protein Phosphorylation | Serine / Threonine Kinases | PKB / AKT | Cancer | Apoptosis | Cancer | Cancer Metabolism | Cancer | Cell Cycle | PI3k/AKT Pathway
Alternative Name:
RAC-PK-alpha Antibody, Protein kinase B alpha Antibody, RAC Antibody, Proto-oncogene c-Akt Antibody, Protein kinase B Antibody, RAC Alpha Antibody, AKT Antibody, EC:2.7.11.1 Antibody, AKT 1 Antibody, PRKBA Antibody, AKT1_HUMAN Antibody, AKT1 Antibody
Category:
Antibodies
Product Type:
Polyclonal Antibody
Immunogen:
Synthetic phospho-peptide from human AKT1 around the phosphorylation site of serine 473 (pSer473).
Immunogen Species:
Human
Applications:
WB, IHC
Host:
Rabbit
Isotype:
IgG
Species Reactivity:
Human, Mouse, Rat
Antibody Dilution:
WB (1:250-1:500); IHC (1:25-1:50); optimal dilutions for assays should be determined by the user.
Purification:
Peptide Affinity Purified
Storage Buffer:
PBS, pH 7.4, 150mM NaCl, 50% glycerol, 0.02% sodium azide
Concentration:
N/A
Specificity:
Detects endogenous levels of AKT1 only when phosphorylated at serine 473 (pSer473).
Storage:
-20ºC
Shipping:
Blue Ice or 4ºC
Certificate of Analysis:
A 1:500 dilution of SPC-1340 was sufficient for detection of AKT1 (pSer473) in 10 µg of human cervical cancer cell line (hela) lysate by ECL immunoblot analysis using goat anti-rabbit as the secondary antibody.
Cellular Localization:
Nucleus, Plasma Membrane, Cell Membrane, Cytoplasm, Cytoskeleton, Ciliary Basal Body, Microtubule, Spindle, Cytosol, Mitochondrion, Nucleoplasm, Cell-Cell Junction, Postsynapse, Protein Complex, Vesicle
Tissue Specificity:
Expressed in prostate cancer and levels increase from the normal to the malignant state (at protein level). Expressed in all human cell types so far analyzed. The Tyr-176 phosphorylated form shows a significant increase in expression in breast cancer
Accession Number:
NP_001014431.1
Gene ID:
207
Swiss-Prot:
P31749
Field of Use:
For in vitro research use only.
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