Additional Information
Size: |
100 µg |
Target: |
AKT1 |
Conjugate: |
RPE |
Research Area: |
Cell Signaling | Protein Phosphorylation | Serine / Threonine Kinases | PKB / AKT | Cell Signaling | Metabolism | Metabolism processes | Cell Signaling | Epigenetics and Nuclear Signaling | Cancer | Apoptosis | Cell Signaling | Metabolism | Metabolis |
Alternative Name: |
RAC-alpha serine/threonine-protein kinase Antibody, Protein Kinase B Alpha Antibody, EC:2.7.11.1 Antibody, AKT1 Antibody, AKT Antibody, MGC99656 Antibody, PKB alpha Antibody, PKB-ALPHA Antibody, AKT 1 Antibody, RAC-PK-alpha Antibody, PRKBA Antibody, |
Category: |
Antibodies |
Product Type: |
Polyclonal Antibody |
Immunogen: |
Synthetic peptide from the mid-protein of Human AKT1 (aa. 100-200) |
Immunogen Species: |
Human |
Applications: |
WB, IHC |
Host: |
Rabbit |
Isotype: |
N/A |
Species Reactivity: |
Human, Mouse |
Antibody Dilution: |
WB (1:1000); IHC (1:50); optimal dilutions for assays should be determined by the user. |
Purification: |
Peptide Affinity Purified |
Storage Buffer: |
PBS pH 7.4, 50% glycerol, 0.09% Sodium Azide |
Concentration: |
1 mg/ml |
Specificity: |
Detects 65 kDa. Band is detected at ~65 kDa, due to post translational modifications. |
Storage: |
-20ºC |
Shipping: |
Blue Ice or 4ºC |
Certificate of Analysis: |
A 1:1000 dilution of SPC-768 was sufficient for detection of AKT1 in 15 µg of mouse Brain cell lysates by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody. |
Cellular Localization: |
Cytoplasm, Nucleus, Cell Membrane |
Tissue Specificity: |
Expressed in prostate cancer and levels increase from the normal to the malignant state (at protein level). Expressed in all human cell types so far analyzed. The Tyr-176 phosphorylated form shows a significant increase in expression in breast cancer |
Accession Number: |
NP_001014431.1 |
Gene ID: |
207 |
Swiss-Prot: |
P31749 |
Field of Use: |
For in vitro research use only. |
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