ALDH5A1 Polyclonal Antibody | E-AB-12961

ALDH5A1 Polyclonal Antibody | E-AB-12961 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: Aldedehyde dehydrogenase 5 family, Aldehyde dehydrogenase 5 family member A1, Aldehyde dehydrogenase 5A1, Aldehyde dehydrogenase family 5 member A1, ALDH5A 1, Aldh5a1, mitochondrial, Mitochondrial succinate semialdehyde dehydrogenase, NAD(+) dependent succinic semialdehyde dehydrogenase, NAD(+)-dependent succinic semialdehyde dehydrogenase, SSADH, SSDH, SSDH, Succinate semialdehyde dehydrogenase, Succinate-semialdehyde dehydrogenase

Application: IHC, ELISA

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Metabolism, Neuroscience, Signal Transduction

Background: This protein belongs to the aldehyde dehydrogenase family of proteins. This gene encodes a mitochondrial NAD(+)-dependent succinic semialdehyde dehydrogenase. A deficiency of this enzyme, known as 4-hydroxybutyricaciduria, is a rare inborn error in the metabolism of the neurotransmitter 4-aminobutyric acid (GABA). In response to the defect, physiologic fluids from patients accumulate GHB, a compound with numerous neuromodulatory properties. Two transcript variants encoding distinct isoforms have been identified for this gene.

Concentration: 0.5 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Synthetic peptide of human ALDH5A1

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: IHC 1:50-1:200

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): N/A

Molecular Weight(Observed): N/A