ALG10B Antibody (C-term) [APR05663G]

ALG10B Antibody (C-term) [APR05663G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This ALG10B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 324-353 amino acids from the C-terminal region of human ALG10B.

Cellular Localisation: Cell membrane {ECO:0000250|UniProtKB:O88788}; Multi-pass membrane protein {ECO:0000250|UniProtKB:O88788}

Molecular Weight: 55448

Clone: Polyclonal

Gene Name: ALG10B

Gene ID: 144245

Function: Putative alpha-1, 2-glucosyltransferase, which adds the third glucose residue to the lipid-linked oligosaccharide precursor for N- linked glycosylation. Transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Glc (2) Man (9) GlcNAc (2) -PP-Dol (By similarity) . When coupled to KCNH2 may reduce KCNH2 sensitivity to classic proarrhythmic drug blockade, possibly by mediating glycosylation of KCNH2 (PubMed:14525949) . Has a role in maintenance of cochlear outer hair cell function (By similarity) .

Summary: Tissue Location: Highly expressed in heart, placenta, liver, kidney and pancreas. Weakly expressed in lung, skeletal muscle and brain

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB

Dilution: WB--1:1000

Synonyms: Putative Dol-P-Glc:Glc (2) Man (9) GlcNAc (2) -PP-Dol alpha-1, 2-glucosyltransferase, Alpha-1, 2-glucosyltransferase ALG10-A, Alpha-2-glucosyltransferase ALG10-B, Asparagine-linked glycosylation protein 10 homolog B, Potassium channel regulator 1, ALG10B, KCR1