ALIX polyclonal Antibody | BS90048

ALIX polyclonal Antibody | BS90048 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Application: WB IHC FC

Application Range: WB:1:500-1:1,000 IHC:1:50-1:200 FC:1:50-1:100

Background: ALG-2-interacting protein (Alix), also designated programmed cell death 6-interacting protein (PDCD6-interacting protein), is a cytoplasmic protein. Alix interacts with apoptosis-associated proteins (ALG-2 and PDCD6) and with the endocytosis-regulator CIN85. Additionally, Alix interacts with the endosomal sorting complexes required for transport (ESCRT) proteins (Tsg101 and CHMP4) and can associate with HIV-1. The endophilins (SH3P4, SH3P8 and SH3P13), enzymes that change curvature of the membrane that are required for early and late steps of coated vesicle formation, also bind to Alix. Alix is involved in the concentration and sorting of cargo proteins of the multivesicular body for incorporation into vesicles.

Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity: ALIX polyclonal Antibody detects endogenous levels of ALIX protein.

Molecular Weight: 96 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: PDCD6-interacting protein, PDCD6IP, AIP1, ALIX, KIAA1375, AIP1, ALG 2 interacting protein 1, ALG-2-interacting protein 1, ALG2 interacting protein X, Alix, Apoptosis linked gene 2 interacting protein X, Dopamine receptor interacting protein 4, DRIP4, Hp95, KIAA1375, MGC17003, PDC6I, PDCD6 interacting protein, PDCD6-interacting protein, PDCD6IP, Programmed cell death 6 interacting protein, Programmed cell death 6-interacting protein,

Immunogen: Recombinant protein

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: ProA affinity purified

Pathway: