Aloe-emodin | B2771

Aloe-emodin is a hydroxyanthraquinone found naturally in aloe plants. It displays antibacterial, antiviral, anti-inflammatory and hepatoprotective effects. Acts as a laxative/cathartic compound; increases the contraction of intestinal smooth muscle by releasing endogenous acetylcholine. Antitumor activity is associated with an increased production of reactive oxygen species (ROS) that, in turn, reduces the mitochondrial transmembrane electrical potential, thus inducing a permeability transition that sets in motion a series of events culminating in cellular apoptosis.

Aloe-emodin is a hydroxyanthraquinone found naturally in aloe plants. It displays antibacterial, antiviral, anti-inflammatory and hepatoprotective effects. Acts as a laxative/cathartic compound; increases the contraction of intestinal smooth muscle by releasing endogenous acetylcholine. Antitumor activity is associated with an increased production of reactive oxygen species (ROS) that, in turn, reduces the mitochondrial transmembrane electrical potential, thus inducing a permeability transition that sets in motion a series of events culminating in cellular apoptosis.

B2771 | Aloe-emodin DataSheet

Alternate Name/Synonyms: 1,8-Dihydroxy 3-hydroxymethylanthraquinone, 3-Hydroxymethylchrysazine,1,8-Dihydroxy-3-(hydroxymethyl)anthraquinone,Rhabarberone

Appearance: Yellow to brownish powder

Formulation:

CAS Number: 481-72-1

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₅H₁₀O₅

Molecular Weight: 270.24

Cell-Permeable?: TRUE

Purity: ≥95%

Solubilities: ~2 mg/ml DMSO

Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.

Country of Origin: USA

Tag Line: An antibacterial, antiviral, and anti-inflammatory agent

MDL Number: MFCD00017373

PubChem CID: 10207

SMILES: C1=CC2=C(C(=C1)O)C(=O)C3=C(C2=O)C=C(C=C3O)CO

InChi: InChI=1S/C15H10O5/c16-6-7-4-9-13(11(18)5-7)15(20)12-8(14(9)19)2-1-3-10(12)17/h1-5,16-18H,6H2

InChi Key: YDQWDHRMZQUTBA-UHFFFAOYSA-N