alpha smooth muscle actin Antibody [G3H10] | 13-917

alpha smooth muscle actin Antibody [G3H10] | 13-917 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: N/A

Immunogen: Recombinant protein of human alpha smooth muscle actin

Research Area: Cell Cycle, Neuroscience, Signal Transduction, Stem Cell

Tested Application: WB, IHC, ICC, IF, Flow

Application: WB: 1:500 - 1:2000
IHC: 1:50 - 1:200
ICC: 1:50 - 1:200
IF: 1:50 - 1:200
Flow: 1:20 - 1:50

Specificiy: N/A

Positive Control 1: A-549

Positive Control 2: HeLa

Positive Control 3: NIH/3T3

Positive Control 4: Mouse heart

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: Observed: 42kDa

Validation: N/A

Isoform: N/A

Purification: Affinity purification

Clonality: Monoclonal

Clone: [G3H10]

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Concentration: N/A

Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.

Alternate Name: ACTA2, ACTSA, actin, alpha 2, smooth muscle, aorta, alpha-cardiac actin, ACTVS, GIG46

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: The protein encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Defects in this gene cause aortic aneurysm familial thoracic type 6. Multiple alternatively spliced variants, encoding the same protein, have been identified.