ALS polyclonal Antibody | BS5607

ALS polyclonal Antibody | BS5607 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB

Application Range: WB: 1:500~1:1000

Background: The Insulin-like growth factor binding proteins, or IGFBPs, are a family of seven proteins that have co-evolved with the IGFs. IGFBPs serve as shuttle molecules for both IGF-I and IGF-II and confer a level of regulation to the IGF signaling system by influencing the bio-availability, concentration and distribution of IGFs in the extracellular environment. In human circulation, the IGF-binging protein complex requires ALS (IGFBP acid-labile subunit), an extracellular protein involved in receptor-ligand binding and cell adhesion. ALS, detected primarily in plasma, is involved in protein-protein interactions that result in the formation of protein complexes.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: ALS polyclonal Antibody detects endogenous levels of ALS protein.

Molecular Weight: ~ 66 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Insulin-like growth factor-binding protein complex acid labile subunit; IGFALS

Immunogen: Synthetic peptide, corresponding to amino acids 177-222 of Human ALS.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: