ALSFTD Antibody | 8469

ALSFTD Antibody | 8469 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: N/A

Immunogen: ALSFTD antibody was raised against a 19 amino acid peptide from near the carboxy terminus of human ALSFTD.
The immunogen is located within amino acids 400 - 450 of ALSFTD.

Research Area: Stem Cell

Tested Application: E, WB, ICC

Application: ALSFTD antibody can be used for the detection of ALSFTD by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunocytochemistry at 10 μg/ml.
Antibody validated: Western Blot in human samples and Immunocytochemistry in mouse samples. All other applications and species not yet tested.

Specificiy: ALSFTD antibody is human, mouse and rat reactive. At least two isoforms are known to exist.

Positive Control 1: Cat. No. 1288 - A20 Cell Lysate

Positive Control 2: Cat. No. 17-208 - A-20 Cell Slide

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: Predicted: 53 kDa
Observed: 52 kDa

Validation: N/A

Isoform: N/A

Purification: ALSFTD Antibody is affinity chromatography purified via peptide column.

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: ALSFTD Antibody is supplied in PBS containing 0.02% sodium azide.

Concentration: 1 mg/mL

Storage Condition: ALSFTD antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year.

Alternate Name: Amyotrophic lateral sclerosis with frontotemporal dementia, chromosome 9 open reading frame 72, C9orf72

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: ALSFTD (C9orf72) is considered to play a role in gender determination (1) . Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, is associated with the chromosome 9 gene encoding endoglin protein, ENG (2) . Familial dysautonomia is also associated with chromosome 9 though through the gene IKBKAP. Notably, chromosome 9 encompasses the largest interferon family gene cluster (3, 4) .