AMACR Polyclonal Antibody | E-AB-10127

AMACR Polyclonal Antibody | E-AB-10127 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: 2 methylacyl CoA racemase, 2-methylacyl-CoA racemase, Alpha methylacyl CoA racemase, Alpha-methylacyl-CoA racemase, Amacr, AMACR, AMACRD, CBAS4, EC 5.1.99.4, Macr1, RACE, RM

Application: WB, IHC, ELISA

Reactivity: Human

Host: Rabbit

Isotype: IgG

Reserch Areas: Cell Biology, Metabolism, Signal Transduction

Background: This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)- and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described. Read-through transcription also exists between this gene and the upstream neighboring C1QTNF3 (C1q and tumor necrosis factor related protein 3) gene.

Concentration: 0.1 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Recombinant protein of human AMACR

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000, IHC 1:25-1:100

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 42 kDa

Molecular Weight(Observed): N/A