AMBP | Alpha-1-microglobulin | AS01 014

AMBP | Alpha-1-microglobulin | AS01 014 | Gentaur UK, US & Europe Distribution

Immunogen: rat alpha-1-microglobulin, full length, recombinant protein, overexpressed in baculovirus-infected insect cells with N-terminal His-tag

Host: Rabbit

Conjugation: N/A

Clonality: Polyclonal

Isotype: N/A

Purity: Serum with 0.04% sodium azide.

Format: Lyophilized

Tested Application: Immunocytochemistry (ICC), Radioimmunoassay (RIA), Western blot (WB)

Related Products: AS01 013 | Anti-alpha-1-microglobulin (abcam BN11.10), mouse monoclonal antibodyAS13 2670 | Anti-A1M | human alpha-1-microglobulin, chicken antibodyAS10 1354 | Anti-B2M | beta-2-microglobulin, goat antibody

Recommended Dilutions: 1 : 5000 (ELISA), 1 : 200 (IHC), 1 : 6000 (RIA), 1 : 2000 (WB)

Molecular weight: 27 kDa

Confirmed Reactivity: Rat

Predicted Reactivity: Mouse

Not reactive in: No confirmed exceptions from predicted reactivity are currently known

Additional Information: N/A

Background: Alpha-1-microglobulin is a 27-kDa glycoprotein with immunosuppressive properties. A gene AMBP in the lipocalin cluster encodes alpha-1-microglobulin together with a Kunitz-type proteinase inhibitor, bikunin. The gene is translated into the alpha-1-microglobulin-bikunin precursor, which is subsequently cleaved and the two proteins are secreted to the blood separately. Alpha-1-microglobulin is found in blood and in connective tissue in most organs. It is most abundant at interfaces between the cells of the body and the environment, such as in lungs, intestine, kidneys and placenta. Alpha 1-microglobulin is an immunomodulatory protein with a broad spectrum of possible clinical applications and seems a promising marker for evaluation of tubular function.

Reconstitution: For reconstitution add 200 µl of sterile water

Storage: Store lyophilized/reconstituted at -20°C; once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.

TAIR Nnumbre: N/A

Category: Other proteins

Research Area: Immunology