840

AMG 232

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SKU:
840-HY-12296-GEN
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NULL315.00

Description

AMG 232

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Additional Information

Size:
5mg
Alternative Names:
N/A
CAS N°:
1352066-68-2
Molecular weight:
568.55
Formula:
C28H35Cl2NO5S
Solubility:
DMSO : ≥ 50 mg/mL (87.94 mM); H2O : < 0.1 mg/mL (insoluble)
Target:
MDM-2/p53
Note:
This product is available in other size, please contact us for more information
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AMG232 is a highly potent MDM2 inhibitor (SPR KD = 0.045 nM, SJSA-1 EdU IC₅₀ = 9.1 nM), with remarkable pharmacokinetic properties and in vivo antitumor activity in the SJSA-1 osteosarcoma xenograft...
26-9556-GEN