Amifostine | 2377

Cell-permeable. A broad spectrum radio- and chemoprotective agent. Prevents chemotherapy-induced apoptosis, upregulates HIF-1α and restores transcriptional activity in specific p53 mutants.

Amifostine is a broad spectrum radio- and chemoprotective agent. Prevents chemotherapy-induced apoptosis, upregulates HIF-1α and restores transcriptional activity in specific p53 mutants.

2377 | Amifostine DataSheet

Alternate Name/Synonyms: S-2(3-Aminopropylamino)-ethylphosphothioic acid; WR2721

Appearance: White solid

Formulation: N/A

CAS Number: 20537-88-6

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₅H₁₅N₂O₃PS

Molecular Weight: 214.22

Cell-Permeable?: Yes

Purity: ≥98% by TLC

Solubilities: H₂O (1 g/ml)

Handling: Protect from light and moisture

Country of Origin: USA

Tag Line: A broad spectrum radio- and chemoprotective agent.

MDL Number: MFCD00233058

PubChem CID: 2141

SMILES: C(CN)CNCCSP(=O)(O)O

InChi: InChI=1S/C5H15N2O3PS/c6-2-1-3-7-4-5-12-11(8,9)10/h7H,1-6H2,(H2,8,9,10)

InChi Key: JKOQGQFVAUAYPM-UHFFFAOYSA-N