AMOT Antibody (N-term) [APR31708G]

AMOT Antibody (N-term) [APR31708G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This AMOT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 240-267 amino acids from the N-terminal region of human AMOT.

Cellular Localisation: Cell junction, tight junction. Note=Localized on the cell surface. May act as a transmembrane protein

Molecular Weight: 118085

Clone: Polyclonal

Gene Name: AMOT

Gene ID: 154796

Function: Plays a central role in tight junction maintenance via the complex formed with ARHGAP17, which acts by regulating the uptake of polarity proteins at tight junctions. Appears to regulate endothelial cell migration and tube formation. May also play a role in the assembly of endothelial cell-cell junctions.

Summary: Tissue Location: Expressed in placenta and skeletal muscle. Found in the endothelial cells of capillaries as well as larger vessels of the placenta.

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB

Dilution: WB--1:1000

Synonyms: Angiomotin, AMOT, KIAA1071