AMPD1 Antibody | 19-094

AMPD1 Antibody | 19-094 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: N/A

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 50-260 of human AMPD1 (NP_001166097.1) .

Research Area: Cancer, Signal Transduction

Tested Application: WB

Application: WB: 1:500 - 1:2000

Specificiy: N/A

Positive Control 1: A375

Positive Control 2: SKOV3

Positive Control 3: A-549

Positive Control 4: Mouse heart

Positive Control 5: Mouse lung

Positive Control 6: Rat skeletal muscle

Molecular Weight: Observed: 80kDa

Validation: N/A

Isoform: N/A

Purification: Affinity purification

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Concentration: N/A

Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.

Alternate Name: AMPD1, adenosine monophosphate deaminase 1 (isoform M) , MAD, MADA, Adenosine monophosphate deaminase-1 (muscle) , OTTHUMP00000059283, MMDD

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: Adenosine monophosphate deaminase 1 catalyzes the deamination of AMP to IMP in skeletal muscle and plays an important role in the purine nucleotide cycle. Two other genes have been identified, AMPD2 and AMPD3, for the liver- and erythocyte-specific isoforms, respectively. Deficiency of the muscle-specific enzyme is apparently a common cause of exercise-induced myopathy and probably the most common cause of metabolic myopathy in the human. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene.