AMPK?1 Antibody | 3951

AMPK is responsible for the regulation of fatty acid synthesis by phosphorylation of acetyl-CoA carboxylase. It also regulates cholesterol synthesis via phosphorylation and inactivation of hormone-sensitive lipase and hydroxymethylglutaryl-CoA reductase. It appears to act as a metabolic stress-sensing protein kinase switching off biosynthetic pathways when cellular ATP levels are depleted and when 5'-AMP rises in response to fuel limitation and/or hypoxia. AMPK alpha1, a member of the Ser/Thr protein kinase family, is a catalytic subunit of AMPK.

3951 | AMPK?1 Antibody DataSheet

Antibody Target: AMPK?1

Target Alternative Name: 5'-AMP-activated protein kinase, AMPK catalytic alpha-1 chain, AMPK alpha-1 chain

Tag Line:

Category: AMPK

Host: Rabbit

Isotype: Rabbit IgG

Species Reactivities: Human, mouse, rat

Immunogen Sequence: Synthetic peptide surroundign amino acid 486 of human AMPK alpha 1

Accession #: NP_006242.5

Gene ID: 5562

Appearance: Colorless liquid

Form: Liquid

Concentration: 0.5 mg/ml

Formulation: 200 µg (0.5 mg/ml) affinity purified rabbit anti-AMPKa1 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal

Purification: Affinity purified

Application: Western blot

Positive Control: Jurkat cell lysate

Application And Usages: The antibody can be used for Western blotting (1–4 µg/ml).

Country of Animal Origin: China

Country of Manufacture: USA

Usage: For Research Use Only! Not to be used in humans.

Handling: The antibody solution should be gently mixed before use.

Western Blot Verified: Verified

Immunocytochemistry Verified: Not Verified

Immunofluorescence Verified: Not Verified

Immunoprecipitation Verified: Not Verified

FACS Verified: Not Verified

ELISA Verified: Not Verified

ChIP Verified: Not Verified

Dot Blot Verified:

Flow Cytometry Verified: Not Verified