AMPK alpha Antibody| F40234-0.08ML/F40234-0.4ML

AMPK alpha Antibody| F40234-0.08ML/F40234-0.4ML | Gentaur UK, US & Europe Distribution

Background: AMPK alpha is the catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. [UniProt]

Format: Purified

Clone: 167CT22.1.6

Host Animal: Mouse

Clonality: Monoclonal (mouse origin)

Isotype: Mouse IgG1, k

Species Reactivity: Human

Predicted Spacies Reactivity: Rat

Application: WB, ELISA

Application Details: Western blot: 1:100-1:500

Application Note: Titration of the AMPK alpha antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Status: Available

Buffer: N/A

Limitation: This AMPK alpha antibody is available for research use only.

Purity: Purified

Immunogen: This AMPK alpha antibody was produced from a mouse immunized with PRKAA1 recombinant protein.

Storage: Aliquot the AMPK alpha antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Localization: N/A