AMPK2 Antibody | 3118

AMPK2 is a catalytic subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (H mgCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. Studies of the mouse counterpart s?ggest that this catalytic subunit may control whole-body insulin sensitivity and is necessary for maintaining myocardial energy homeostasis during ischemia.

3118 | AMPK2 Antibody DataSheet

Antibody Target: AMPK2

Target Alternative Name: EC 2.7.11.1, AMPK alpha-2 chain, PRKAA2

Tag Line:

Category: AMPK

Host: Rabbit

Isotype: Rabbit IgG

Species Reactivities: Human

Immunogen Sequence: Synthetic peptide selected from the center region of human AMPK2

Accession #: P54646

Gene ID: 5563

Appearance: Colorless liquid

Form: Liquid

Concentration: 0.25 mg/ml

Formulation: 100 µg (0.25 mg/ml) purified rabbit Ig polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

Purification:

Application: ELISA, Western blot

Positive Control:

Application And Usages: The antibody can be used for ELISA (0.25 µg/ml) and Western blotting (2.5 – 5.0 µg/ml).

Country of Animal Origin: USA

Country of Manufacture: USA

Usage: For Research Use Only! Not to be used in humans.

Handling: The antibody solution should be gently mixed before use.

Western Blot Verified: Verified

Immunocytochemistry Verified: Not Verified

Immunofluorescence Verified: Not Verified

Immunoprecipitation Verified: Not Verified

FACS Verified:

ELISA Verified: Verified

ChIP Verified: Not Verified

Dot Blot Verified:

Flow Cytometry Verified: Not Verified