Amrinone | B2465

Amrinone is a potent phosphodiesterase 3 (PDE3) inhibitor (IC₅₀ = 19.5 µM). It increases developed tension and contractile force in isolated cat papillary muscle. It also displays positive inotropic effects, increasing the rate and force of heart contraction in anesthetized and unanesthetized dogs.

Amrinone is a potent phosphodiesterase 3 (PDE3) inhibitor (IC₅₀ = 19.5 µM). It increases developed tension and contractile force in isolated cat papillary muscle. It also displays positive inotropic effects, increasing the rate and force of heart contraction in anesthetized and unanesthetized dogs.

B2465 | Amrinone DataSheet

Alternate Name/Synonyms: 5-amino-[3,4'-bipyridin]-6(1H)-one; WIN 40,680

Appearance: Beige to yellow solid

Formulation:

CAS Number: 60719-84-8

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₀H₉N₃O

Molecular Weight: 187.2

Cell-Permeable?: True

Purity: ≥98% by HPLC

Solubilities: 0.5 mg/ml in DMSO

Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.

Country of Origin: USA

Tag Line: A phosphodiesterase 3 (PDE3) inhibitor

MDL Number: MFCD00083228

PubChem CID: 3698

SMILES: C1=CN=CC=C1C2=CNC(=O)C(=C2)N

InChi: InChI=1S/C10H9N3O/c11-9-5-8(6-13-10(9)14)7-1-3-12-4-2-7/h1-6H,11H2,(H,13,14)

InChi Key: RNLQIBCLLYYYFJ-UHFFFAOYSA-N