ANAPC2 (Apc2) monoclonal Antibody | MB62144

ANAPC2 (Apc2) monoclonal Antibody | MB62144 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Human, Mouse, Rat

Application: FC, IF, WB

Application Range: WB 1:2000, IF 1:100, FLOW 1:100

Background: A large protein complex, termed the anaphase-promoting complex (APC), or the cyclosome, promotes metaphase-anaphase transition by ubiquitinating its specific substrates such as mitotic cyclins and anaphase inhibitor, which are subsequently degraded by the 26S proteasome. Biochemical studies have shown that the vertebrate APC contains eight subunits. The composition of the APC is highly conserved in organisms from yeast to humans. The product of this gene is a component of the complex and shares sequence similarity with a recently identified family of proteins called cullins, which may also be involved in ubiquitin-mediated degradation. [provided by RefSeq, Jul 2008]

Storage & Stability: PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Specificity: anaphase promoting complex subunit 2

Molecular Weight: 93.6 kDa (Predicted)

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: APC2

Immunogen: Full length human recombinant protein of human ANAPC2 (NP_037498) produced in HEK293T cell.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Pathway: N/A