Andrastin A, Aspergillus fumigatus | 2149

A protein farnesyl transferase inhibitor. Displays antitumor properties. Inhibits the efflux of anticancer drugs from multidrug-resistant cancer cells.

Andrastin A, Aspergillus fumigatus is a protein farnesyl transferase inhibitor. Displays antitumor properties. Inhibits the efflux of anticancer drugs from multidrug-resistant cancer cells.

2149 | Andrastin A, Aspergillus fumigatus DataSheet

Alternate Name/Synonyms:

Appearance: Off-white solid

Formulation: N/A

CAS Number: 174232-42-9

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₈H₃₈O₇

Molecular Weight: 486.61

Cell-Permeable?: Yes

Purity: ≥95% by HPLC

Solubilities: DMSO or EtOH

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A protein farnesyl transferase inhibito

MDL Number: N/A

PubChem CID: 496693

SMILES: CC1C(=O)C2(C(=CC3C(C2(C1=O)C(=O)OC)(CCC4C3(CCC(C4(C)C)OC(=O)C)C=O)C)C)C

InChi: InChI=1S/C28H38O7/c1-15-13-19-25(6,28(23(33)34-8)22(32)16(2)21(31)26(15,28)7)11-9-18-24(4,5)20(35-17(3)30)10-12-27(18,19)14-29/h13-14,16,18-20H,9-12H2,1-8H3/t16?,18?,19-,20?,25?,26+,27+,28?/m0/s1

InChi Key: GRBXNADBNJGZRK-BCMOVVIDSA-N