ANGPTL7 Antibody (C-term) [APR14087G]

ANGPTL7 Antibody (C-term) [APR14087G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This ANGPTL7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 315-346 amino acids from the C-terminal region of human ANGPTL7.

Cellular Localisation: Secreted.

Molecular Weight: 40018

Clone: Polyclonal

Gene Name: ANGPTL7

Gene ID: 10218

Function: Has a role in the formation and organization of the extracellular matrix. In the eye, it functions as a mediator of dexamethasone-induced matrix deposition in the trabecular meshwork, the tissue responsible for the outflow of the ocular aqueous humor and for the maintenance of intraocular pressure (PubMed:21199193) . Is a negative regulator of angiogenesis in the cornea, and plays a major role in maintaining corneal avascularity and transparency (PubMed:25622036) .

Summary: Tissue Location: Higly expressed in the cornea (at protein level) (PubMed:11682471) . Expression is restricted to the stromal layer (PubMed:11682471) . Also detected at the junction between the corneal stromal layer and the conjuctiva. Not detected in the sclera (PubMed:11682471) .

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB, IHC-P, FC

Dilution: WB--1:1000 IHC-P--1:100~500 FC--1:10~50

Synonyms: Angiopoietin-related protein 7, Angiopoietin-like factor, Angiopoietin-like protein 7, Cornea-derived transcript 6 protein, ANGPTL7, CDT6