ANGPTL7 Antibody [Kairos 108-4] | 36-056

ANGPTL7 Antibody [Kairos 108-4] | 36-056 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Human

Homology: N/A

Immunogen: Recombinant human full length ANGPTL7.

Research Area: Cancer, Stem Cell

Tested Application: E, IHC, WB

Application: ELISA: (direct or indirect: 1:2, 000-1:5, 000) . Immunohistochemistry: (paraffin sections (1:100) ) . Western blot: (1:2, 000-1:5, 000 using ECL. Suggested blocking and dilution buffer is PBST with 0.05% Tween 20 and 5% skim milk. Suggested incubation time is 1 hour at room temperature) . Optimal conditions should be determined individually for each application.

Specificiy: Recognizes human ANGPTL7. Detects a band of ~45kDa by Western blot. Weakly cross-reacts with human ANGPTL7-CCD.

Positive Control 1: N/A

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: N/A

Validation: N/A

Isoform: N/A

Purification: N/A

Clonality: Monoclonal

Clone: Kairos 108-4

Isotype: IgG1, kappa

Conjugate: Unconjugated

Physical State: Liquid

Buffer: Liquid. 0.2um-filtered solution in PBS, pH 7.4. Contains no preservatives.

Concentration: 1 mg/ml

Storage Condition: Stable for at least 1 year after receipt when stored at -20˚C.

Alternate Name: Angiopoietin-like Protein 7; Cornea-derived Transcript 6 Protein

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: ANGPTL7 is expressed in various tissues and regulates angiogenesis. Human ANGPTL7 was characterized as a potent target gene of the WNT/ beta-catenin signaling pathway, and is a pharmacogenomics target in the fields of oncology and regenerative medicine. Overexpression of ANGPTL7 increases collagen expression and might exert a pathogenic role in glaucoma.