Annexin V, human recombinant | 1005

Reagent for detecting early stages of apoptosis. During apoptosis, phosphatidylserine (PS) is translocated from the cytoplasmic face of the plasma membrane to the cell surface. Annexin V has a strong, Ca2+-dependent affinity for PS and therefore is used as a probe for detecting apoptosis. The unlabeled Annexin V reagent can be conjugated to any tag of choice for detection of apoptosis. The reagent can also be used in competition binding experiments to compete with tagged annexin V conjugates. Annexin V-FITC, -Cy3, -Cy5, -EGFP, -PE, PE/CY5, and -Biotin Labels are also available separately.

1005 | Annexin V human recombinant DataSheet

Biomolecule/Target: Annexin V

Synonyms: Annexin V, human recombinant

Alternates names: Anchorin CII, Annexin V, Annexin-5, Calphobindin I, Endonexin II, Lipocortin V, Placental anticoagulant protein 4, lacental anticoagulant protein I, Thromboplastin inhibitor, Vascular anticoagulant-alpha, PP4, ANX5, ENX2, ANXA5, Annexin A5, Annexin-5, Annexin V, Lipocortin V, Endonexin II, Calphobindin I, CBP-I, Placental anticoagulant protein I, PAP-I, Placental anticoagulant protein 4, VAC-alpha, Anchorin CII.

Taglines: A reagent for detecting early stages of apoptosis

NCBI Gene ID #: 9255

NCBI Gene Symbol: AIMP1

Gene Source: N/A

Accession #: Q12904

Recombinant: Yes

Source: N/A

Purity by SDS-PAGEs: 98%

Assay: SDS-PAGE

Purity: N/A

Assay #2: HPLC

Endotoxin Level: N/A

Activity (Specifications/test method): N/A

Biological activity: Determined by its ability to induce apoptosis in MCF-7 cells using a concentration range of 20-40 ng/ml.

Results: N/A

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: 18.3 kDa

Concentration: 1 mg/ml

Appearance: Liquid

Physical form description: Liquid form (1 mg/ml in PBS, pH 7.4)

Reconstitution Instructions: Reconstitute in HO to a concentration of 0.1-1.0 mg/ml. This solution can then be diluted into other aqueous buffers

Amino acid sequence: N/A