ANP32C polyclonal Antibody | BS5864

ANP32C polyclonal Antibody | BS5864 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB

Application Range: WB: 1:500~1:1000

Background: ANP32C (acidic (leucine-rich) nuclear phosphoprotein 32 family, member C), also known as PP32R1 (phosphoprotein 32-related protein 1) or tumorigenic protein pp32r1, is a 234 amino acid protein that contains 4 leucine-rich repeats and belongs to the ANP32 family. ANP32C shares 87.7% amino acid sequence identity with ANP32A, a tumor suppressor that inhibits a variety of cancers, such as prostate and breast cancers. Although similar to ANP32A, ANP32C is tumorigenic and is expressed in activated stem cells, such as mobilized CD34+ cells and cord blood CD34+ cells, but not in resting bone marrow CD34+ cells. ANP32C is also expressed in a variety of neoplastic cell lines, mainly in prostatic adenocarcinoma cell lines, but not in normal protastic tissue, and may also modulate the oncogenic potential of human prostate cancer.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: ANP32C polyclonal Antibody detects endogenous levels of ANP32C protein.

Molecular Weight: ~ 27 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Acidic leucine-rich nuclear phosphoprotein 32 family member C; Phosphoprotein 32-related protein 1; Tumorigenic protein pp32r1; PP32R1

Immunogen: Synthetic peptide, corresponding to amino acids 161-206 of Human ANP32C.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: