Anti- ACADVL Antibody | FNab00068

Anti- ACADVL Antibody | FNab00068 | Gentaur UK, US & Europe Distribution

Form: liquid

Purification: Immunogen affinity purified

Purity: ≥95% as determined by SDS-PAGE

Host: Rabbit

Clonality: polyclonal

Clone ID: N/A

Isotype: IgG

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: Very long-chain acyl-CoA dehydrogenase (VLCAD) is one of four flavoproteins which catalyze the initial step of the mitochondrial b-oxidation spiral. It belongs to the acyl-CoA dehydrogenase family and is a homodimer of a 71-kDa polypeptide. The molecular mass of the nondenatured trypsinized VLCAD is 98 kDa, by gel filtration chromatography, indicating that it is a homodimer of the 48 kDa (tryptic digest) polypeptide (PMID:9461620) . Defects in ACADVL are the cause of acyl-CoA dehydrogenase very long chain deficiency (ACADVLD) . It has 2 isoforms (70 kDa and 68 kDa ) produced by alternative splicing and a transit peptide.

Immunogen: acyl-Coenzyme A dehydrogenase, very long chain

synonyms: ACAD6, ACADVL, LCACD, VLCAD

Molecular weight (observed) : 48 kDa, 68-73 kDa

Reactivity Species: Human, Mouse, Rat

Tested Application: ELISA, WB, IHC

Recomended Dillution : WB: 1:200-1:2000; IHC: 1:20-1:200

Research Area: Metabolism