Anti- ACC1 Antibody | FNab00077

Anti- ACC1 Antibody | FNab00077 | Gentaur UK, US & Europe Distribution

Form: liquid

Purification: Immunogen affinity purified

Purity: ≥95% as determined by SDS-PAGE

Host: Rabbit

Clonality: polyclonal

Clone ID: N/A

Isotype: IgG

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: ACACA (Acetyl-CoA carboxylase 1, ACC), also named as ACAC, ACC1 and ACCA, belongs to the biotin containing enzyme family. It catalyzes the synthesis of malonyl-CoA, which is an intermediate substrate playing a pivotal role in the regulation of fatty acid metabolism and energy production. ACACA is involved in the biosynthesis of fatty acids, and malonyl-CoA produced is used as a building block to extend the chain length of fatty acids by fatty acid synthase (FAS) (PMID:19900410) . It has 4 isoforms produced by alternative promoter usage with the molecular weight between 260 kDa and 270 kDa.

Immunogen: acetyl-Coenzyme A carboxylase alpha

synonyms: ACACA Synonyms ACAC, ACACA, ACC, ACC1, ACCA, Acetyl CoA carboxylase 1

Molecular weight (observed) : 270 kDa

Reactivity Species: Human, Mouse, Rat

Tested Application: ELISA, WB

Recomended Dillution : WB: 1:200-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200

Research Area: Cardiovascular, Metabolism