Anti- AP1, JUN, P39 Antibody | FNab00455

Anti- AP1, JUN, P39 Antibody | FNab00455 | Gentaur UK, US & Europe Distribution

Form: liquid

Purification: Immunogen affinity purified

Purity: ≥95% as determined by SDS-PAGE

Host: Rabbit

Clonality: polyclonal

Clone ID: N/A

Isotype: IgG

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation. Involved in activated KRAS-mediated transcriptional activation of USP28 in colorectal cancer (CRC) cells (PubMed:24623306) . Binds to the USP28 promoter in colorectal cancer (CRC) cells (PubMed:24623306) .

Immunogen: jun oncogene

synonyms: Activator protein 1, AP 1, AP1, c Jun, JUN, jun oncogene, P39, Proto oncogene c Jun, Transcription factor AP 1

Molecular weight (observed) : 40 kDa

Reactivity Species: Human, Mouse, Rat

Tested Application: ELISA

Recomended Dillution : WB: 1:500-1:1000; IHC: 1:20-1:200; IF: 1:50-1:500

Research Area: Signal Transduction, Metabolism, Cardiovascular, Immunology, Cancer, Neuroscience