Anti- APH1A Antibody | FNab00481

Anti- APH1A Antibody | FNab00481 | Gentaur UK, US & Europe Distribution

Form: liquid

Purification: Immunogen affinity purified

Purity: ≥95% as determined by SDS-PAGE

Host: Rabbit

Clonality: polyclonal

Clone ID: N/A

Isotype: IgG

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral proteins such as Notch receptors and APP (beta-amyloid precursor protein) . It probably represents a stabilizing cofactor for the presenilin homodimer that promotes the formation of a stable complex.

Immunogen: anterior pharynx defective 1 homolog A

synonyms: APH 1A, Aph 1alpha, APH1A, CGI 78, Gamma secretase subunit APH 1A, PSF, UNQ579/PRO1141

Molecular weight (observed) : 30 kDa

Reactivity Species: Human, Mouse, Rat

Tested Application: ELISA, WB, IHC, IF

Recomended Dillution : WB: 1:500 - 1:1000

Research Area: Neuroscience, Immunology, Cardiovascular, Metabolism