Anti- ARAP3 Antibody | FNab00523

Anti- ARAP3 Antibody | FNab00523 | Gentaur UK, US & Europe Distribution

Form: liquid

Purification: Immunogen affinity purified

Purity: ≥95% as determined by SDS-PAGE

Host: Rabbit

Clonality: polyclonal

Clone ID: N/A

Isotype: IgG

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: Phosphatidylinositol 3, 4, 5-trisphosphate-dependent GTPase-activating protein that modulates actin cytoskeleton remodeling by regulating ARF and RHO family members. Is activated by phosphatidylinositol 3, 4, 5-trisphosphate (PtdIns (3, 4, 5) P3) binding. Can be activated by phosphatidylinositol 3, 4-bisphosphate (PtdIns (3, 4, 5) P2) binding, albeit with lower efficiency. Acts on ARF6, RAC1, RHOA and CDC42. Plays a role in the internalization of anthrax toxin.

Immunogen: ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3

synonyms: CENTD3

Molecular weight (observed) : 45 kDa

Reactivity Species: Human

Tested Application: ELISA, WB, IHC

Recomended Dillution : IHC: 1:20-1:200

Research Area: Signal Transduction