710
Anti- ARRDC3 Antibody | FNab00608
- SKU:
- 710-FNab00608-GEN
- Availability:
- In Stock - Delivery within a week
Description
Anti- ARRDC3 Antibody | FNab00608 | Gentaur UK, US & Europe Distribution
Form: liquid
Purification: Immunogen affinity purified
Purity: ≥95% as determined by SDS-PAGE
Host: Rabbit
Clonality: polyclonal
Clone ID: N/A
Isotype: IgG
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: Adapter protein that plays a role in regulating cell-surface expression of adrenergic receptors and probably also other G protein-coupled receptors (PubMed:20559325, PubMed:21982743, PubMed:23208550) . Plays a role in NEDD4-mediated ubiquitination and endocytosis af activated ADRB2 and subsequent ADRB2 degradation (PubMed:20559325, PubMed:23208550) . May recruit NEDD4 to ADRB2 (PubMed:20559325) . Alternatively, may function as adapter protein that does not play a major role in recruiting NEDD4 to ADRB2, but rather plays a role in a targeting ADRB2 to endosomes (PubMed:23208550) .
Immunogen: arrestin domain containing 3
synonyms: ARRDC3, arrestin domain containing 3, KIAA1376, TLIMP
Molecular weight (observed) : 46 kDa
Reactivity Species: Human
Tested Application: ELISA, WB
Recomended Dillution : WB: 1:500-1:1000; IF: 1:10-1:100
Research Area: Metabolism