Anti- BRMS1 Antibody | FNab00960

Anti- BRMS1 Antibody | FNab00960 | Gentaur UK, US & Europe Distribution

Form: liquid

Purification: Immunogen affinity purified

Purity: ≥95% as determined by SDS-PAGE

Host: Rabbit

Clonality: polyclonal

Clone ID: N/A

Isotype: IgG

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: Transcriptional repressor. Down-regulates transcription activation by NF-kappa-B by promoting the deacetylation of RELA at 'Lys-310'. Promotes HDAC1 binding to promoter regions. Down-regulates expression of anti-apoptotic genes that are controlled by NF-kappa-B. Promotes apoptosis in cells that have inadequate adherence to a substrate, a process called anoikis, and may thereby inhibit metastasis. May be a mediator of metastasis suppression in breast carcinoma.

Immunogen: breast cancer metastasis suppressor 1

synonyms: N/A

Molecular weight (observed) : 28 kDa

Reactivity Species: Human

Tested Application: ELISA, WB, IHC, IF, IP

Recomended Dillution : WB: 1:500-1:2000

Research Area: Epigenetics