Anti- Caspase 9 Antibody | FNab01296

Anti- Caspase 9 Antibody | FNab01296 | Gentaur UK, US & Europe Distribution

Form: liquid

Purification: Immunogen affinity purified

Purity: ≥95% as determined by SDS-PAGE

Host: Rabbit

Clonality: polyclonal

Clone ID: N/A

Isotype: IgG

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein can undergo autoproteolytic processing and activation by the apoptosome, a protein complex of cytochrome c and the apoptotic peptidase activating factor 1; this step is thought to be one of the earliest in the caspase activation cascade. This protein is thought to play a central role in apoptosis and to be a tumor suppressor. Alternative splicing results in multiple transcript variants.This antibody can recognize the pre- and cleaved- caspase 9.

Immunogen: caspase 9, apoptosis-related cysteine peptidase

synonyms: APAF 3, APAF3, Apoptotic protease Mch 6, CASP 9, CASP9, Caspase 9, CASPASE 9c, Caspase9, Caspase-9, ICE LAP6, ICE like apoptotic protease 6, MCH6

Molecular weight (observed) : 17kDa/36kDa/46kDa

Reactivity Species: Human, Mouse, Rat

Tested Application: ELISA, IF, IHC, IP, WB, FC

Recomended Dillution : WB: 1:200 - 1:200; IHC: 1:50 - 1:200; IF: 1:50 - 1:100

Research Area: Metabolism