Anti-Cathepsin D Polyclonal Antibody | AB0043

Goat Anti-Human Cathepsin D IgG Polyclonal Antibody | AB0043 | Antibodies

Overview: Goat polyclonal antibody to Cathepsin D. Cathepsin D is a lysosomal aspartic protease of the pepsin family. Acid protease active in intracellular protein breakdown. It is composed of a dimer of disulphide-linked heavy and light chains, both produced from a single protein precursor. It is involved in the pathogenesis of several diseases such as breast cancer and possibly Alzheimer disease.

Other Names: ceroid-lipofuscinosis, CLN10; CPSD, CTSD, lysosomal aspartyl protease, lysosomal aspartyl peptidase, neuronal 10 antibody.

Other Names: ceroid-lipofuscinosis, CLN10; CPSD, CTSD, lysosomal aspartyl protease, lysosomal aspartyl peptidase, neuronal 10 antibody.

Concentration: 3 mg/ml

Antibody Type: Primary

Target Type: Anti-Cathepsin D

Accession Number: ENSG00000117984

Host Species: Goat

Immunogen Species: Human

Immunogen Type: Recombinant protein

Immunogen: Purified recombinant peptide derived from within residues 275 aa to the C-terminus of human Cathepsin D produced in E. coli.

Isotype: IgG

Clonality: Polyclonal

Confirmed Reactive Species: Human, mouse, rat, bovine, canine, chicken/avian, donkey, feline, goat, guinea pig, hamster, horse, porcine, rabbit, sheep, simian, other

Specificity Detail: This antibody gives a positive signal in the following human (Jurkat, HT1080, HUH, MDA-MB-231, ARPE19, SH-SY5Y), canine (MDCK) and monkey (COS-7) whole cell lysates.

Buffer: PBS, 20% glycerol and 0.05% sodium azide

Purification: Epitope affinity purified

Conjugation: Unconjugated

Format: N/A

Application: WB, IF, IHC-P, IHC-F, IEM

Concentration/Dilution: WB:1:250-1:1,000, IF:1:50-1:200, IHC-P:1:50-1:200, IHC-F:1:50-1:200, IEM:1:50-1:200

Storage: N/A

References: 1. Romagnoli M, Bresson L, Di-Cicco A, et al. Development 2020 Jan. PMID:31988184, 2. Pelkonen L, Sato K, Reinisalo M, et al. Mol Pharm 2017 Mar 6. PMID:28112518