Anti-CD161/KLRB1 Antibody | A2309

The KLRB1 protein, also known as CD161, is expressed by natural killer cells and is involved in the regulation of NK cell function. Certain subpopulations of T cells also express CD161 on their surface. CD161 inhibits NK cell cytotoxicity, and T cells that express CD161 may be linked to inflammation and immunological disorders. Expression of CD161 on T cells has been linked to glioma and other human cancer types. Inactivation of CD161 has been shown recently to mediate the killing of glioma cells and exact anti-tumor functions, making it an intriguing therapeutic target.

A2309 | Anti-CD161/KLRB1 Antibody DataSheet

Antibody Target: Human CD161/KLRB1

Target Alternative Name: Killer Cell Lectin Like Receptor B1; Natural Killer Cell Surface Protein P1A; NKR-P1A; CLEC5B; Killer Cell Lectin-Like Receptor Subfamily B Member 1; C-Type Lectin Domain Family 5 Member B; HNKR-P1A; NKR-P1; NKRP1A; CD161 Antigen; KLRB1; NKR

Tag Line: Plays an inhibitory role on natural killer cell cytotoxicity

Category: GM-CSF

Host: Rabbit

Isotype: IgG

Species Reactivities: Human Mouse

Immunogen Sequence: Fusion protein of Human KLRB1

Accession #: Q12918

Gene ID: 3820

Appearance: Liquid

Form: Rabbit polyclonal

Concentration:

Formulation: In PBS pH 7.4, 0.05% sodium azide, 40% glycerol

Purification: Antigen affinity purification

Application: ELISA Western Blotting Immunohistochemistry (IHC)

Positive Control:

Application And Usages:

Country of Animal Origin: USA

Country of Manufacture: USA

Usage: For Research Use Only! Not to be used in humans.

Handling: The antibody solution should be gently mixed before use.

Western Blot Verified: FALSE

Immunocytochemistry Verified: TRUE

Immunofluorescence Verified: FALSE

Immunoprecipitation Verified: FALSE

FACS Verified: FALSE

ELISA Verified: FALSE

ChIP Verified: TRUE

Dot Blot Verified: FALSE

Flow Cytometry Verified: FALSE