Anti- CD3 epsilon Antibody | FNab01459

Anti- CD3 epsilon Antibody | FNab01459 | Gentaur UK, US & Europe Distribution

Form: liquid

Purification: Protein A+G purification

Purity: ≥95% as determined by SDS-PAGE

Host: Mouse

Clonality: monoclonal

Clone ID: 2E4

Isotype: IgG1

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: CD3 is a complex of proteins that directly associates with the T cell receptor (TCR) . The TCR/CD3 complex of T-lymphocytes consists of either a TCR alpha/beta or TCR gamma/delta heterodimer coexpressed at the cell surface with the invariant subunits of CD3 labeled gamma, delta, epsilon, zeta, and eta. The TCR recognizes antigens bound to major histocompatibility complex (MHC) molecules. TCR-mediated peptide-MHC recognition is transmitted to the CD3 complex, leading to the intracellular signal transduction. CD3 is considered to be a pan-T cell marker for detection of normal and neoplastic T cells. This anti-CD3 is a monoclonal antibody directed against the epsilon chain of human CD3 molecule.

Immunogen: CD3e molecule, epsilon (CD3-TCR complex)

synonyms: CD3, CD3 epsilon, CD3E, CD3-epsilon, T3E, TCRE

Molecular weight (observed) : 23 kDa

Reactivity Species: Human

Tested Application: ELISA, WB, IHC

Recomended Dillution : WB: 1:2000 - 1:20000; IHC: 1:1000 - 1:10000; IF: 1:50 - 500

Research Area: Cancer, Immunology, Signal Transduction