Anti- CD47 Antibody | FNab01486

Anti- CD47 Antibody | FNab01486 | Gentaur UK, US & Europe Distribution

Form: liquid

Purification: Immunogen affinity purified

Purity: ≥95% as determined by SDS-PAGE

Host: Rabbit

Clonality: polyclonal

Clone ID: N/A

Isotype: IgG

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: Has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. Plays an important role in memory formation and synaptic plasticity in the hippocampus (By similarity) . Receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. Interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation. May play a role in membrane transport and/or integrin dependent signal transduction. May prevent premature elimination of red blood cells. May be involved in membrane permeability changes induced following virus infection.

Immunogen: CD47 molecule

synonyms: CD47, CD47 molecule, IAP, Leukocyte surface antigen CD47, MER6, OA3, Protein MER6

Molecular weight (observed) : 47-55 kDa

Reactivity Species: Human

Tested Application: ELISA, WB, IP

Recomended Dillution : WB: 1:500-1:1000; IHC: 1:50-1:500

Research Area: Stem Cells, Immunology, Cardiovascular