Anti-CDX2 monoclonal Antibody | MB62208

Anti-CDX2 monoclonal Antibody | MB62208 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Human, Mouse, Rat, Dog

Application: IF, WB

Application Range: WB 1:1000

Background: The level and beta-cell specificity of insulin gene expression are regulated by a set of nuclear proteins that bind to specific sequences within the promoter of the insulin gene (INS; MIM 176730) and interact with RNA polymerase to activate or repress transcription. The proteins LMX1 (MIM600298) and CDX3 are homeodomain proteins that bind an A/T-rich sequence in the insulin promoter and stimulate its transcription.

Storage & Stability: PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Specificity: caudal type homeobox 2

Molecular Weight: 33.5 kDa (Predicted)

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: CDX-3; CDX2/AS; CDX3

Immunogen: Recombinant protein expressed in E.coli corresponding to amino acids 1-313 of human CDX2

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Pathway: N/A