Anti- CNGA3 Antibody | FNab01796

Anti- CNGA3 Antibody | FNab01796 | Gentaur UK, US & Europe Distribution

Form: liquid

Purification: Immunogen affinity purified

Purity: ≥95% as determined by SDS-PAGE

Host: Rabbit

Clonality: polyclonal

Clone ID: N/A

Isotype: IgG

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: Visual signal transduction is mediated by a G-protein coupled cascade using cGMP as second messenger. This protein can be activated by cyclic GMP which leads to an opening of the cation channel and thereby causing a depolarization of cone photoreceptors. Induced a flickering channel gating, weakened the outward rectification in the presence of extracellular calcium, increased sensitivity for L-cis diltiazem and enhanced the cAMP efficacy of the channel when coexpressed with CNGB3 (By similarity) . Essential for the generation of light-evoked electrical responses in the red-, green-and blue sensitive cones.

Immunogen: cyclic nucleotide gated channel alpha 3

synonyms: CNCG3

Molecular weight (observed) : 98 kDa

Reactivity Species: Human

Tested Application: ELISA, WB, IF

Recomended Dillution : WB: 1:500-1:2000

Research Area: Neuroscience, Signal Transduction