Anti- Collagen Type I Antibody | FNab09910

Anti- Collagen Type I Antibody | FNab09910 | Gentaur UK, US & Europe Distribution

Form: liquid

Purification: protein A+G purified

Purity: ≥95% as determined by SDS-PAGE

Host: Mouse

Clonality: monoclonal

Clone ID: 3D7

Isotype: IgG1

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: This gene encodes the pro-alpha2 chain of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIB, recessive Ehlers-Danlos syndrome Classical type, idiopathic osteoporosis, and atypical Marfan syndrome. Symptoms associated with mutations in this gene, however, tend to be less severe than mutations in the gene for the alpha1 chain of type I collagen (COL1A1) reflecting the different role of alpha2 chains in matrix integrity. Three transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene.

Immunogen: collagen, type I, alpha 2

synonyms: Alpha 2 type I collagen, COL1A2, Collagen alpha 2 (I) chain, Collagen Type I, collagen, type I, alpha 2, OI4

Molecular weight (observed) : N/A

Reactivity Species: Human

Tested Application: ELISA, WB, IF, IP

Recomended Dillution : IHC: 1:2000 - 1:8000

Research Area: Stem Cells, Cardiovascular