Anti- Collagen Type VI Antibody | FNab01846

Anti- Collagen Type VI Antibody | FNab01846 | Gentaur UK, US & Europe Distribution

Form: liquid

Purification: Immunogen affinity purified

Purity: ≥95% as determined by SDS-PAGE

Host: Rabbit

Clonality: polyclonal

Clone ID: N/A

Isotype: IgG

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: Type VI Collagen is a major structural component of microfibrils. Type VI Collagen was found to be present throughout the connective tissue and in the extracellular matrix of cultured fibroblasts (PMID: 6723253) . It is a heterotrimer composed of three different chains: alpha-1 (VI), alpha-2 (VI), and alpha-3 (VI) or alpha-5 (VI) or alpha-6 (VI) . The alpha-1 (VI) chain is encoded by COL6A1 gene. Mutations in this gene result in Bethlem myopathy and Ullrich congenital muscular dystrophy.

Immunogen: collagen, type VI, alpha 1

synonyms: COL6A1, collagen 6A1, Collagen alpha 1 (VI) chain, collagen, type VI, alpha 1, OPLL

Molecular weight (observed) : 140 kDa

Reactivity Species: Human, Mouse, Rat

Tested Application: ELISA, WB, IHC

Recomended Dillution : WB: 1:500-1:1000; IP: 1:500-1:1000; IHC: 1:50-1:200; IF: 1:20-1:200

Research Area: Signal Transduction