Anti- CPNE1 Antibody | FNab01926

Anti- CPNE1 Antibody | FNab01926 | Gentaur UK, US & Europe Distribution

Form: liquid

Purification: Immunogen affinity purified

Purity: ≥95% as determined by SDS-PAGE

Host: Rabbit

Clonality: polyclonal

Clone ID: N/A

Isotype: IgG

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: Calcium-dependent phospholipid-binding protein that plays a role in calcium-mediated intracellular processes (PubMed:14674885) . Involved in the TNF-alpha receptor signaling pathway in a calcium-dependent manner (PubMed:14674885) . Exhibits calcium-dependent phospholipid binding properties (PubMed:9430674, PubMed:19539605) . Plays a role in neuronal progenitor cell differentiation; induces neurite outgrowth via a AKT-dependent signaling cascade and calcium-independent manner (PubMed:23263657, PubMed:25450385) . May recruit target proteins to the cell membrane in a calcium-dependent manner (PubMed:12522145) . May function in membrane trafficking (PubMed:9430674) . Involved in TNF-alpha-induced NF-kappa-B transcriptional repression by inducing endoprotease processing of the transcription factor NF-kappa-B p65/RELA subunit (PubMed:18212740) . Also induces endoprotease processing of NF-kappa-B p50/NFKB1, p52/NFKB2, RELB and REL (PubMed:18212740) .

Immunogen: copine I

synonyms: CPN1

Molecular weight (observed) : N/A

Reactivity Species: Human

Tested Application: ELISA, WB, IHC, FC, IF

Recomended Dillution : N/A

Research Area: Metabolism