Anti-Cripto 1 Antibody | A1672

GPI-anchored cell membrane protein involved in Nodal signaling. Cell-associated TDGF1 acts as a Nodal coreceptor in cis. Shedding of TDGF1 by TMEM8A modulates Nodal signaling by allowing soluble TDGF1 to act as a Nodal coreceptor on other cells. Could play a role in the determination of the epiblastic cells that subsequently give rise to the mesoderm.

A1672 | Anti-Cripto 1 Antibody DataSheet

Antibody Target: Cripto 1

Target Alternative Name: CRIPTO; Teratocarcinoma-derived growth factor 1; Cripto-1 growth factor; CRGF; Epidermal growth factor-like cripto protein CR1

Tag Line: Polyclonal antibody to detect endogenous levels of Cripto 1 in human, mouse and rat samples

Category: Stem Cells

Host: Rabbit

Isotype: Rabbit IgG

Species Reactivities: Human, Mouse, Rat

Immunogen Sequence: A synthesized peptide derived from human Cripto 1

Accession #: P13385

Gene ID: 6997

Appearance: Colorless liquid

Form: Liquid

Concentration: 1 mg/ml

Formulation: In phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02% sodium azide and 50% glycerol

Purification: Affinity purified

Application: WB,IHC, ELISA

Positive Control: WB: NCCIT lysate, IHC: Human lung tissue

Application And Usages: WB 1:500-1:2000 IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Country of Animal Origin: USA

Country of Manufacture: USA

Usage: For Research Use Only! Not to be used in humans.

Handling: The antibody solution should be gently mixed before use.

Western Blot Verified: Verified

Immunocytochemistry Verified: Verified

Immunofluorescence Verified: Not Verified

Immunoprecipitation Verified: Not Verified

FACS Verified: Not Verified

ELISA Verified: Not Verified

ChIP Verified: Not Verified

Dot Blot Verified: Not Verified

Flow Cytometry Verified: Not Verified