Anti- CYP7B1 Antibody | FNab02177

Anti- CYP7B1 Antibody | FNab02177 | Gentaur UK, US & Europe Distribution

Form: liquid

Purification: Immunogen affinity purified

Purity: ≥95% as determined by SDS-PAGE

Host: Rabbit

Clonality: polyclonal

Clone ID: N/A

Isotype: IgG

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: Oxysterol 7alpha-hydroxylase that mediates formation of 7-alpha, 25-dihydroxycholesterol (7-alpha, 25-OHC) from 25-hydroxycholesterol (PubMed:10588945) . Plays a key role in cell positioning and movement in lymphoid tissues: 7-alpha, 25-dihydroxycholesterol (7-alpha, 25-OHC) acts as a ligand for the G protein-coupled receptor GPR183/EBI2, a chemotactic receptor for a number of lymphoid cells (By similarity) .

Immunogen: cytochrome P450, family 7, subfamily B, polypeptide 1

synonyms: CBAS3, CP7B, CYP7B1, Cytochrome P450 7B1, Oxysterol 7 alpha hydroxylase, SPG5A

Molecular weight (observed) : 50-55 kDa

Reactivity Species: Human, Mouse

Tested Application: ELISA, WB, IHC

Recomended Dillution : WB: 1:500-1:2000; IHC: 1:50-1:200; IF: 1:20-1:200

Research Area: Cardiovascular, Metabolism