Anti- DNMT3L Antibody | FNab02486

Anti- DNMT3L Antibody | FNab02486 | Gentaur UK, US & Europe Distribution

Form: liquid

Purification: Immunogen affinity purified

Purity: ≥95% as determined by SDS-PAGE

Host: Rabbit

Clonality: polyclonal

Clone ID: N/A

Isotype: IgG

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: Catalytically inactive regulatory factor of DNA methyltransferases. It is essential for the function of DNMT3A and DNMT3B. Activates DNMT3A and DNMT3B by binding to their catalytic domain. Accelerates the binding of DNA and AdoMet to the methyltransferases and dissociates from the complex after DNA binding to the methyltransferases. Recognizes unmethylated histone H3 lysine 4 (H3K4) and induces de novo DNA methylation by recruitment or activation of DNMT3.

Immunogen: DNA (cytosine-5-) -methyltransferase 3-like

synonyms: N/A

Molecular weight (observed) : 44kd and 70kd

Reactivity Species: Human

Tested Application: ELISA, WB, IP

Recomended Dillution : WB: 1:500-1:2000

Research Area: Epigenetics, Metabolism, Developmental biology