Anti- DYNC1LI1 Antibody | FNab02585

Anti- DYNC1LI1 Antibody | FNab02585 | Gentaur UK, US & Europe Distribution

Form: liquid

Purification: Immunogen affinity purified

Purity: ≥95% as determined by SDS-PAGE

Host: Rabbit

Clonality: polyclonal

Clone ID: N/A

Isotype: IgG

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. Probably involved in the microtubule-dependent transport of pericentrin. Is required for progress through the spindle assembly checkpoint. The phosphorylated form appears to be involved in the selective removal of MAD1L1 and MAD1L2 but not BUB1B from kinetochores.

Immunogen: dynein, cytoplasmic 1, light intermediate chain 1

synonyms: DNCLI1

Molecular weight (observed) : 57-60 kDa

Reactivity Species: Human

Tested Application: ELISA, WB, IF

Recomended Dillution : WB: 1:500-1:2000

Research Area: Signal Transduction, Metabolism